Grail

  • Menlo Park, CA, USA
Grail Menlo Park, CA, USA
Jan 18, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com GRAIL is seeking Research Associates I/II for the LabOps Core Services team, who will be primarily responsible for ensuring the efficient execution of GRAIL assays in support of Research and Development activities.  The ideal candidate is a detail-oriented, dynamic team player with experience in both automated and manual NGS assay execution. The candidate will be expected to partner with many functions of our organization - Automation, Product Development, LIMS, Quality, Supply Chain, Biosample Operations, and Clinical Lab - to ensure the successful completion of R&D projects and general Operational support.  You Will: Execute on forecasted R&D experiments ranging from reagent evaluation and qualification to general data generation activities.Execute on automated and manual sample preparation and NGS assays.Be responsible for accurately recording work performed per GLP, including results and methodology.Aid in the investigation of potential quality issues (both internal and external) and work with Quality to resolve Corrective and Preventive Actions (CAPA).  Ensure laboratory activities are performed in compliance with procedures and safety guidelines when handling, storing and disposing of hazardous or bio-hazardous materials.Have excellent personal task management skills and a high level of self-motivation. Your Background Should Include: B.S required in a relevant field.1+ years of experience in Next Generation Sequencing assays and workflows preferred.Experience with Automated sample preparation workflows is a plus.Familiarity with basic molecular biology laboratory techniques including but not limited to (e.g. pipetting, SPRI, PCR, qPCR).Familiarity with nucleic acids extraction techniques and quantification devices (e.g., Nanodrop, Bioanalyzer, Fragment Analyzer, ddPCR) is a plus.Excellent teamwork and collaboration skills.Outstanding written and verbal communication skills.  Self-directed, innovative, and creative thinker.General computer skills and proficiency in GSuite.
Grail Menlo Park, CA, USA
Jan 18, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com GRAIL is seeking a Supervisor to manage the LabOps Core Services team, who will be primarily responsible for ensuring the efficient execution of GRAIL assays in support of Research and Development activities. The candidate will be leading the development and growth of a new team that will need to be staffed and trained on a variety of GRAIL assays. The ideal candidate is a detail-oriented, dynamic team player with deep experience in both automated and manual NGS assay execution. The candidate will be expected to partner with many functions of our organization - Automation, Product Development, LIMS, Quality, Supply Chain, Biosample Operations, and Clinical Lab - to forecast for upcoming activities, delegate work to direct reports, and be instrumental in the implementation and operation of a Core Services lab that provides a modular platform for planning and efficiently executing on R&D projects and general Operational support.   You Will: Lead the execution of forecasted R&D experiments ranging from reagent evaluation and qualification to general data generation activities.Become an expert on current production assays and legacy manual workflows.Coordinate the forecasting and execution of experiments with various stakeholders including R&D, Biosample Operations, and Supply Chain. Be responsible for accurately recording work performed per GLP.Investigate potential quality issues (both internal and external) and work with Quality to resolve Corrective and Preventive Actions (CAPA).  Ensure laboratory activities are performed in compliance with procedures and safety guidelines when handling, storing and disposing of hazardous or bio-hazardous materials.Have excellent personal task management skills and a high level of self-motivation.Be a demonstrated manager having hired, trained, and led high performing teams in a fast paced production-like environment. Your Background Should Include: B.S required, advanced degree strongly preferred in a relevant field.2+ years of experience in Next Generation Sequencing assays and workflows.Experience with Automated sample preparation workflows.Experience developing and executing QC test workflows is a plus.Proficient with basic molecular biology laboratory techniques including but not limited to (e.g. pipetting, SPRI, PCR, qPCR).Familiarity with nucleic acids extraction techniques and quantification devices (e.g., Nanodrop, Bioanalyzer, Fragment Analyzer, ddPCR).Excellent teamwork and collaboration skills.Outstanding written and verbal communication skills.  Self-directed, innovative, and creative thinker.General computer skills and proficiency in GSuite.
Grail Menlo Park, CA, USA
Jan 18, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com GRAIL is seeking a Director, Key Accounts to establish and integrate GRAIL products and services, with health systems and other key accounts. This individual will possess the capabilities to fully represent GRAIL’s overall product portfolio and technological platform at a health system and/or payor level and evolve our value proposition to surpass the account’s needs.  Developing business relationships with key influencers and executives while creating an engaging and sustainable customer experience with our key accounts is critical to success. It is anticipated that GRAIL will hire several of these positions, geographically dispersed across the United States (with specific geographies to be determined.) You Will: Network with various stakeholders across the account and in the market and develop a breadth and depth of relationships within each account to ensure an understanding of each account’s objectives, goals, drivers and challengesProfile key accounts to understand the quality and economic flow, and define precision medicine/genomics decision-making processesUnderstand and anticipate the account's goal and needs across the system of care and to identify opportunities to develop and deliver resourcesPrepare integrated account plans to help identify challenges to successful customer interactions, implementing the right internal mechanism as appropriate to mitigate themWork to ensure the account’s needs are appropriately met to ensure GRAIL delivers a patient-focused customer experienceCollaborate with payer access and marketing team to bring the voice of the customer in development of GRAIL product and technology value propositionsDevelop and own key accounts through strong collaboration and strategic coordination with other GRAIL roles that also support the accountsManage account’s evolution and any potential impact to GRAIL’s strategy and monitor and ensure alignment across GRAIL on each Account’s business positionUnderstand current state and emerging trends in business operations affecting practice management such as Annual Report, payer initiatives, EMR capabilities, and clinical care pathway developmentMaintain a future focus on emerging trends and patient care needs in cancer early detection, uncovering and reporting underlying issues that may inform broad or account-specific strategiesEnsure access to GRAIL's products are achieved and in a compliant manner Your Background Will Include: BS/BA degree preferably with a science/ healthcare major and/or advanced science, public health or allied healthcare degreeMinimum of 10  years with demonstrated strong account management experience leading substantive revenue generating accountsDemonstrated success implementing product and service solutions with health systems or health plans in prior rolesAbility to build and develop customer relationships including the ability to effectively represent GRAIL and its products to senior levels of management and key thought leadersInnovative thinking and exceptional business acumen, analytical and problem-solving skillsStrong understanding of compliance-related concepts including the laws, regulations and policies that govern marketing and sales activities and the importance of compliance in all job-related functionAbility to understand, distill and communicate complex scientific and public health related conceptsExperience in partnership models with health systems and payersHealth system, oncology and diagnostic experience preferredTrack record of working with objective based goals and success in achieving them
Grail Menlo Park, CA, USA
Jan 18, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com GRAIL is seeking a Research Associate for the LabOps Manufacturing Sciences andTechnology team (MSAT), who will be primarily responsible for materials quality control (QC) and associated tasks. The ideal candidate is a detail-oriented, exceptional team player with hands-on laboratory experience. The candidate will be expected to partner with many functions of our organization - Automation, Product Development, LIMS, Quality, and Clinical Lab - to identify systems limitations, implement process improvements, write documentation, and be instrumental in the implementation and operation of an internal QC system. You Will: Execute on high complexity, functional testing of in-house prepared and externally acquired reagents. Monitor the manufacturing of assay materials.Coordinate material readiness timing with Supply Chain and material transfers to the Clinical Lab for final material release testing.Support root cause analysis for materials failing QC.Document existing processes and review and maintain existing QC documentation.Investigate potential quality issues (both internal and external) and work with Quality to resolve Corrective and Preventive Actions (CAPA). Uphold QC activity compliance with current Quality Systems including, but not limited to CLIA, CAP, and FDA regulatory guidelines.Be an expert in the materials used in the current production assays. Maintain the reagent retain policy.Assist, when applicable, in Manufacturing activities. Your Background Should Include: B.S. in a relevant field required.1+ years hands-on laboratory experience, NGS experience is preferred.Experience with automated sample preparation workflows is a plus.Proficient with basic molecular biology laboratory techniques.Excellent teamwork and collaboration skills.Ability to multitask as needed in a start-up environment.Outstanding written and verbal communication skills.Self-directed, innovative, and creative thinker.General computer skills and proficiency in GSuite.
Grail Menlo Park, CA, USA
Jan 17, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com You Will: Develop, prepare, and manage submission of regulatory applications and related supplements and amendments for innovative products.In close collaboration with cross-functional teams, contribute to regulatory strategies for assigned programs and work with internal R&D, Product and Quality teams on execution.As a representative of Regulatory Affairs, work on cross-functional teams and projects, especially those related to software, machine learning, digital health, and artificial intelligence, and provide regulatory guidance and education through the interpretation of laws, regulations, policies, procedures, guidelines, and compliance requirements.Interact directly with regulatory health authorities.Work with others in Regulatory Affairs to train on regulatory requirements and collect and disseminate intelligence on evolving laws, requirements, policies, and trends as relevant to the business. Your Background Will Include: 5+ years of regulatory affairs experience M.S. or Ph.D. in the field of software, physics, engineering, science, or a relevant discipline Experience advising on software regulation Experience in executing regulatory strategy for assigned programsExceptional writing skills with experience in drafting and submitting regulatory submissions to regulatory authorities Cross-functional problem solving skillsExceptional communication and presentation skillsAbility to communicate regulatory requirements to cross-functional teamsExperience in creating and maintaining a corporate culture of complianceQuality System Regulation (and ISO 13485) knowledge preferredRAC credential preferred 
Grail Menlo Park, CA, USA
Jan 17, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com Be the technical point of contact for our ERP application (NetSuite): architect, design, build and deliver optimized and scalable NetSuite solutions including customizations, scripting (2.0), integrations and support case resolutions for customization defects . Stay ahead of the new NetSuite features and functionality, and provide recommendations for improvements. Perform technical design/code reviews and audits to ensure design objectives are met and standards are followed. Work with management product managers and finance business partners to scope work and produce deliverable estimates. Adapt to changing priorities of the business and seek out ways to develop new skills. Balance multiple concurrent projects and contending priorities. You Will: Design and implement technology solutions in NetSuite according to business and stakeholder requirements from various departmentsPast experience with large scale implementations NetSuite/Oracle, Coupa and their integrations through Mulesoft/BoomiAbility to create/edit saved searches/dashboards and write and review SuiteScripts from scratchProvide hands-on support for NetSuite users and build solutions for optimizing the usability of the system via SuiteScript, SuiteTalk, SuiteFlow, and SuiteCloudEnsure systems integrations with NetSuite are built for scale to align with the growth of the company while maintaining accuracy and completeness of data flowing into NetSuite from our LIMS, Apttus, Coupa, and other third-party systemsWork with the platform engineering teams and systems analysts on automating data integrations with NetSuiteBuilding custom workflows using the UI based workflow builderInteract with NetSuite software vendors and external consultants and collaborate to guide problems to resolutionClear communication and orchestration of technical development, documentation and overall SDLCWorking knowledge of Jira, Jenkins, GitHub and overall Devops experienceHands-on experience with Hybrid/Agile project methodologyDemonstrated ability to create order out of chaos, with minimal oversightOther duties/tasks as assigned based on business priorities and goals. E.g. user maintenance/Report development Your Background Includes: Javascript and SuiteScript, SuiteTalk, Suitelets, SuiteBuilder, SuiteFlow, Ability to write and review SuiteScripts (1.0 & 2.0) from scratch. Extensive understanding of SuiteFlow, SuiteScript, SuiteBuilder, Workflows and Map-ReduceKnowledge of JavaScript, Node.js, SOAP, REST, XML, HTML and JSON technologies. Expertise with Boomi and prior experience in building NetSuite integrationsEngineering experience in Java, Golang/Ruby and SQL Qualifications:Bachelor’s Degree in Information Systems, Computer Science or a related field is required5-7 years of hands-on experience building technology solutions for NetSuite using SuiteScript and SuiteTalk
Grail Menlo Park, CA, USA
Jan 17, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com In this role, you will head up a team of bioinformatics scientists to analyze some of the largest, richest biological datasets in the world to find biological signals and patterns and guide our assays and develop new methods for future products. You will work with diverse teams including software, clinical, operations, research, product development, and external collaborators. Your work will result in exciting discoveries in cancer biology, impactful publications, and potential future products. You will: Lead, develop, and manage a team of bioinformatics scientists.Develop new bioinformatics approaches for analysis of large-scale genomics datasets and application development.Collaborate with various internal teams including software, clinical, operations, research, and product development.Act as bioinformatics functional lead for GRAIL’s external scientific collaborators.End-to-end analysis that includes design, data gathering, processing, analysis, iteration with stakeholders, and presentation of results.Promulgate approaches and build tools that preserve scientific rigor and quality.Maintain an active external scientific presence. Your Background Includes: Ph.D. in Bioinformatics, Computational Biology, Statistics, Biological Sciences, Cancer Biology, Genetics, Genomics, Computer Science, Physics, or equivalent preparation and experience.Demonstrated ability to manage bioinformatics teams, provide technical leadership, perform translational research, and lead and contribute to cross functional projects. Proven track record of proven contributions demonstrated by highly cited publications, impactful tools, products, or data sets used by the scientific community, presentations at international conferences, and awards.Must-have 7 years relevant experience in positions of increasing responsibility.Deep understanding of modern statistical and machine learning tools for analysis of genomics datasets. Demonstrated expertise in at least one programming language (R, Python, Go, C++).Proficiency in Linux environment, version control tools, and reproducible research practices. Technical leadership and self-direction, willingness to both teach others and learn new techniques.Effective written and verbal communication skills.
Grail Menlo Park, CA, USA
Jan 16, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com The Staff or Senior Staff Biostatistician provides statistical expertise and leadership to clinical development and post-market projects. This position will partner with key internal and external stakeholders to design, analyze, and interpret clinical studies in support of GRAIL’s product development, commercialization, and payer’s reimbursement. You Will: Provide strategic input for and contribute to GRAIL product development, post-launch activities, and payer’s reimbursement.Represent the Biostatistics function and collaborate with internal and external thought leaders in the design, analysis, interpretation, and publication of clinical studies.Contribute to protocols, statistical analysis plans, study reports, presentations, and publications of clinical studies.  Contribute to the development of innovative analysis methodologies, including cutting edge machine learning algorithmsWork on significant and unique issues that require exercising independent judgment and developing/adapting methodology.Stay abreast of industry and academic developments in the Statistical Genomics and Immuno-oncology field and apply to clinical study design and analysis. Your Background Will Include: Ph.D. in Biostatistics or equivalent with 5+ years of experience (or MS with 7+ years) in academia or industry. Molecular diagnostics or pharmaceutical industry experience preferred.Ph.D. with 10+ years of experience will be considered at the Senior Staff level.Strong knowledge of theoretical and applied statisticsOutstanding verbal, writing, and presentation skills with a strong ability to influence and communicate effectively throughout all levels of the organization and externally.Demonstrated success leading the statistical portion of a clinical development program in the industry.Knowledge of applicable regulatory rules and guidelines, e.g., ICH, GCP, HIPAA.Experience programming in R or SAS.Strong team player with a demonstrated track record of success in the cross­-functional team environment.Experience with machine learning techniques is a plusExperience with genomic data analysis is a plus
Grail Menlo Park, CA, USA
Jan 15, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com The Process Monitoring Supervisor will oversee and manage Production Process Monitoring activities to sustain high quality data generation and resolution of production assay issues. The high complexity nature of the work requires excellent attention to detail, effective written and verbal communication skills, the ability to multitask and be flexible with tasks and schedules, and the ability to work independently in a team environment. This role will also be required to provide input into the development of tools required to enable efficient process monitoring. Cross functional interaction with the Product Development, Automation, Research, Bioinformatics, Software and Materials Management groups will be required to report issues and find resolutions for the Laboratory Operations team.  You Will: Use solid understanding of GRAIL’s various production assays to daily monitor all production assay activities.Track performance metrics and investigate any deviations and data quality concerns.Track and document all production assay issue resolutions and provide data analysis support to the Clinical Lab function of Laboratory Operations.Bridge between multiple teams to quickly resolve production assay issues.Interface cross-functionally on multiple complex issues in parallel.Effectively request resources across projects to ensure maximum efficiency.Recommend changes to procedures to improve efficiency.Facilitate and manage weekly Process Monitoring meetings. Your Background Should Include: B.S required, advanced degree strongly preferred in a relevant area.Minimum 5 years of experience in Next Generation Sequencing assays and workflows in a production setting.Experience with Automated sample preparation workflows.Experience using R, Python, Java, etc for data analysis; development of dashboards and reports is a plus.Proven leadership and management skills.Excellent teamwork and collaboration skills.Outstanding written and verbal communication skills.Ability to manage multiple priorities in a growing company.Effective process and project management skills.Self-directed, innovative, and creative thinker.Professional knowledge of scientific principles and concepts.Experience in Word, Excel, Project and PowerPoint or equivalent required.Working knowledge of program/project management software preferred.PMP certification a plus.Familiarity with clinical laboratory operations is a plus.
Grail Menlo Park, CA, USA
Jan 15, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com As a key member of the Quality team, the Associate Director,  Quality Supplier Management will design, create and drive process excellence for development and execution of the strategy and plan for the company Quality Supplier program; with key responsibilities crossing materials and reagents, consumables, instrument, equipment, information systems, clinical operations business functions.  This position is also responsible for providing direction to the Supplier Chain Management functional area to ensure high-quality, safe and effective products and/or services that are compliant with regulatory expectations. The individual will direct the supplier’s operational efforts (quality, effectiveness, and efficiency) of the applicable functional area in support of compliance and business goals. This position will develop individual talent, functional leaders, and other external resources to meet the challenges of the organization. You Will: Develop supplier capabilities to support the needs of the business, meet or exceed the technology, quality and capacity goals of each commodity space.Drive the development of supplier strategy for each product group with an emphasis on the ability to influence, evaluate and publish a written strategy to all executive stakeholders, develop and implement metrics to ensure accountability.Coordinate needs for GRAIL’s device from internal stakeholders and document Company strategy assuring that execution matches the Quality Plan of Record.Create, execute, and monitor supplier process controls based on part classification.Create the business processes, workflows procedures, and policies to capture part and supplier classification, approvals, and changes to key operational part attribute to ensure an effective Supplier Quality System.Work closely with engineering to develop cost models, supplier capability tables and ensure that short and long-term supplier selections are made consistent with strategy.Establish Quality Agreement procedures and templates specific to CTOs, CROs, materials, and components.Negotiate, draft, implement and maintain Quality Agreements (QTA) with suppliers of goods and services.Manage Supplier profiles (Supplier Change Notifications, Change Controls related to Suppliers, Quality Agreements).Manage Supplier Complaints and Supplier Corrective Action Report (SCARs), GRAIL Supplier CAPAs, Deviations, including conducting cross-functional Root-Cause Analysis activities.Maintain an effective approved Supplier list and Supplier Audit Schedule.Establish a supplier change notification agreements for material/component suppliers operating without Quality Agreements.Perform supplier audits (develop audit plan, conduct quality audit, prepare audit reports, communicate findings, audit responses, compliance assessment including compliance risk to support Supply Chain/ Manufacturing/Material Management/ Material Qualification/ QC.Participate in Internal & External Audits including responses to Regulatory bodies inquiries.Provide coaching/training to QA, product development key stakeholders personnel on Quality Systems requirements and process improvement methodologies.  Your Background Should Include: A minimum of a Bachelor of Science Degree in Engineering or scientific field with at least 10+ years direct-related experience in outsourcing and working with contract manufacturing with at least 5 years in a manufacturing environment (molecular diagnostic instrument or related industry is preferred); A minimum of 5 years of experience in cross-functional leadership, organizational development and clear ability to implement change through influence.ASQ’s Certified Supplier Quality Professional (CSQP) or other equivalent certification is preferred.Experience with world-class manufacturing techniques (Lean, Six Sigma, Kanban, Kaizen, etc.) is highly desired.Experience in working in Biotech and/or Medical Device manufacturing industry and managing new product development across the product lifecycle of conceptualization, design controls, customer interface, QMS excellence, installed base management and end of the product life is highly desired.Experience in working in highly regulated environments with FDA on the PMA track is highly desired.Has a proven track record of delivering results and is action-oriented.Excellent communication, influencing skills and ability to gain buy-in for initiatives.Excellent verbal, written, communication and proficient computer skills, specifically with statistical software and Microsoft Office Suite including Word, Excel, PowerPoint.Travel will be required between 30 - 40% of the time, both domestically and internationally. Must be able to work in a biohazard environment and comply with safety policies and standards outlined in the Safety Manual.
Grail Menlo Park, CA, USA
Jan 15, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com The Staff Automation and Systems Engineer coordinates, manages and implements technical engineering support for a variety of process automation hardware, software applications, and laboratory instruments  for a smooth production lab operations. The Staff Automation and Systems Engineer will primarily mentor team members, interact with scientists, software developers and end users to  transfer and continuously improve to implement robust automated solutions into day-to-day laboratory operations. The ideal candidate will be experienced in liquid handling robotic platforms, software integration and supporting complex systems as well as setting  up support process in regulated production setting working with cross functional teams. You Will: Manage supporting, troubleshooting and improving existing automated systems activities in regulated production labMentor team members and be the technical lead for support of lab automated platformsTake a lead in implementing process and workflow systems to support complex automated process in regulated production labOptimize existing automated processes to improve efficiency, throughput, robustness and qualitySupport the installation, facility acceptance test and validation of the new and or revised equipment, automated systems to ensure quality compliance and user requirements.Author, execute and document test plans and Standard Operating Procedures (SOPs) for automated workflowsCoordinate with different cross functional team members and execute projects in a timely mannerRecommend and implement changes to ensure ongoing high-quality performance of laboratory equipmentMonitor and evaluate new and emerging technologies in laboratory automation systems Your Background Will Include: B.S. or M.S. in molecular biology, chemistry, engineering or a related disciplineMinimum 5-7 years hands on experience in integrated automated solutions and liquid handling platforms Minimum 3 years experience supporting regulated labs Experience managing cross functional projects and implementing new workflow processesProficiency in both writing and optimizing scripts on automated liquid handling platforms (e.g., Hamilton, Tecan, Beckman, etc.,)Experience with LIMS and software integrationExperience in mentoring team members is desirableExperience with writing and executing test protocolsWorking knowledge of clinical laboratory operations and activitiesAnalytical, creative thinker, ability to solve problemsEffective organizational and time management skillsHighly energetic and self-motivated. Able to work independently and as part of a teamExcellent written and communication skills
Grail Menlo Park, CA, USA
Jan 15, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com The Associate Director (AD) of Clinical Compliance - has overall responsibility for and oversight of the GCP Audit Program. This will include audit process development/maintenance, risk assessments, tracking, audit metrics and development of the annual audit plan.  This position will require the candidate to have a high level of knowledge and experience with the Good Clinical Practice (GCP) audit process, Internal / Investigator Site / Vendor audits, drug/device development regulations and standards, clinical operations and data management processes, and regulatory inspections.  A thorough understanding of the audit process, applicable regulations and standards, metrics development, interpretation and reporting, issue management and regulatory authority inspections.  It is important that this person have the ability to successfully, and independently, work across functions and incorporate broad viewpoints into the deliverables. You Will: Lead the GCP Audit Program – Internal, Investigator Site and Vendor auditsConduct and oversee GCP audits as requiredSupport Clinical Issue Management and follow upDevelopment, interpretation and reporting of audit metricsLead and support Inspection readiness and preparation activities Work with teams and stakeholders to address compliance concernsSupport Quality Management ReviewsAbility to participate in and/or lead departmental or interdepartmental strategic initiatives independentlyWork cross-functionally to create shared solutions Your Background Includes: 6+ years of relevant experience preferredBachelor’s degree or equivalent in the life sciences or related field required; advanced degree preferredExperience conducting all types of GCP audits, Computer System Validation (CSV) audit experience also desiredExperience overseeing GCP audit consultantsExperience developing and maintaining a GCP audit program and developing audit responses
Grail Menlo Park, CA, USA
Jan 15, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com In this role, you will analyze some of the largest, richest biological datasets in the world to find biological signals and patterns and guide our assays, bioinformatic pipelines, and product strategies. Working closely with scientists, clinicians, and engineers, you will develop inference to investigate the biology of cell free nucleic acid  tumor biology and how that relates to classification performance. You will execute statistical analyses operating across GRAIL’s data sets, public data, and data from collaborators in academia and industry. Your analyses will result in exciting discoveries in cancer biology, impactful publications, and products for early detection of cancer. You Will: Modeling and analysis of large, complex genomics datasets using machine learning and statistical methods to generate biological insights. Perform end-to-end analysis that include data gathering, processing, analysis, iteration with stakeholders, and presentation of results.Interact cross-functionally with other teams including software, clinical, operations, research, product development, and external collaborators.Promulgate analyses that reinforce scientific rigor and quality and which maintain GRAIL’s statistical culture. Your Background Includes: Ph.D. in Bioinformatics, Computational Biology, Statistics, Biological Sciences, Cancer Biology, Genetics, Genomics, Computer Science, Physics, or equivalent preparation and experience.Proven track record of strong contributions demonstrated by highly cited publications, impactful tools, products, or data sets used by the scientific community, presentations at international conferences, and awards.Preferred, 3 years relevant experience in positions of increasing responsibility.Deep understanding of modern statistical and machine learning tools for analysis of genomics datasets. Demonstrated ability to apply these skills to uncover new biological insights from large genomics datasets.Demonstrated expertise in at least one programming language (R, Python, Go, C++), proficiency in Linux environment, version control tools, and reproducible research practices. Self-direction, willingness to both teach others and learn new techniques.Effective written and verbal communication skills.
Grail Menlo Park, CA, USA
Jan 14, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com Position Summary Reporting to the Head of Marketing, the Director of Customer Experience (CX) plays a strategic role in defining the vision for and delivering an industry-leading customer experience for GRAIL’s multi-cancer early detection product. The Director of CX will be accountable for making data-driven decisions for shaping how we engage patients and physicians end-to-end in order to support our mission of helping detect cancer early when it can be cured. You Will: Assess the customer needs at each touchpoint in the consumer and physician journey for the multi-cancer early cancer product. Define the experience and offerings required to ensure a seamless experience that will drive customer adoption, utilization and satisfaction with the product.Scope the organizational needs required to support the components of the offering. Drive the development and implementation of the offerings. Develop, evaluate, and implement strategies to evaluate success and gather and respond to patient and physician feedback regarding the offering. Partner with Commercial, Product Management, Software and other key stakeholders in the concepting, design, development, delivery, and tracking of success of the customer experience.Serve as the organizational expert in best practices for CX.  Provide thought leadership on emerging technology to enhance the delivery of our product and customer experience.Develop and engages employees to promote teamwork and an inclusive, high-performing culture. Your Background Will Include: 6+ years CX leadership experience supporting the launch of consumer-facing products.4+ years' experience leading teams responsible for the delivery of product consumer experiences.Bachelor’s degree or equivalent in Business, Marketing, or other CX-related field required; advanced degree preferred.Strong customer-centric orientation.Experience leading the vision and delivery of CX in a healthcare environment.Demonstrated success leading a team uncovering valuable customer insights in order to recommend and implement practices that positively impact our customers.Deep expertise in product design as it applies to CX, customer journeys, buy paths & customer segmentation.Demonstrated experience developing and implementing CX strategies and roadmaps.Ability to motivate a team to work effectively under in fast-paced and changing environment.
Grail Menlo Park, CA, USA
Jan 14, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com Join a highly organized and exceptionally agile administrative team driven by GRAIL’s mission: to detect cancer early, when it can be cured. We work behind the scenes making crucial contributions via those we support. This role requires independent thinking, highly-developed interpersonal skills, a friendly and helpful demeanor, and a solution-oriented approach. GRAIL is seeking an experienced Executive Assistant (Contract) who can partner with an executive in managing projects and activities.  This is a contract role: 6mo+ You will: Partner with senior management, actively managing and optimizing their complex calendarsMonitor projects and goal progress for the departmentPerform as both an individual contributor and collaborate with the broader extended team Suggest ways to run a more efficient function / troubleshoot malfunctionsField requests for meetings and coordinate various aspects of interdepartmental communication as necessaryTake action items in meetings, coordinate with senior manager to determine due dates, and follow up with individualsPrepare meeting materials and presentationsExercise judgement within narrowly defined practices or policies to find solutionsIn depth knowledge of company operationsManage and plan domestic and international travel, prepare expense reports, coordinate team meetings, events and off-sitesAd hoc projects as assigned 3-5+ years experience executive administrative  support, including complex calendar managementExcellent project management, prioritization and organizational skills.Ability to multitask efficiently in a fast-paced and dynamic environmentRemains calm under pressure with exceptional attention to detail with the ability to roll with punches/not take things personal Takes initiative: anticipating, addressing and resolving potential needs, conflicts, or challengesAbility to quickly learn and implement new procedures, software, and technologiesAbility to communicate cross-functionally and externally with easeBelieves that no task is too big or too smallB.A./B.S. degree or equivalent practical experience
Grail Menlo Park, CA, USA
Jan 09, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com Position Summary As a Staff Process Engineer at GRAIL you will support development, engineering, and research projects by contributing to an evolving, dynamic product development team. The ideal candidate will possess extensive experience developing laboratory processes and equipment test methods to support assay development and manufacturing processes necessary for high-throughput sample screening, molecular testing or IVD development in a regulated, highly cross-functional environment.  Responsibilities include developing processes to support reagent manufacturing and characterization processes, development of instrument and system performance characterization and qualification protocols. Supporting the creation and execution of process and equipment validation, including writing plans, protocols, and reports. Candidate should possess strong troubleshooting skills and be a team player. You Will: Develop laboratory test processes necessary to enable high-throughput sample screening though next generation sequencing assays.Lead planning, preparation, execution, and documentation for qualification of a diverse set of equipment used in various approaches for DNA analysis and NGS workflow.Develop IQ/OQ/PQ strategy for instruments, including processes for requalification and preventative maintenance.Develop automated reagent manufacturing processes and support, internal and external technical transfer projects.Troubleshoot and optimize automated assays and test methods.Develop and execute characterization studies on a broad range of instrumentation including liquid handlers, mixers, incubators, thermocyclers, plate readers, etc.Experience with engineering statistical models and uncertainty analysis.Develop verification plans for process transfer to operations teams and manage internal transfer activities. Write plans, reports, work instructions and SOPs for development and transfer activities.Provide technical leadership of project teams performing development work per GLP and transition to Design Control process. Evaluate and present experimental data analysis, methodology, and results at technical meetings.Participate in project planning as part of a cross-functional team.Ensure laboratory activities are performed in compliance with procedures and safety guidelines when handling, storing and disposing of hazardous or biohazardous materials. Your Background Will Include: Demonstrated success in technical proficiency, problem solving creativity and collaboration with others. Experience in IVD Design, Design Control or assay development in a regulated environment is desired.PhD in biochemistry, molecular biology, or related field preferred with 6+ years of industry experience or BS/MS with 8+ years of industry experience.Molecular diagnostics or pharmaceutical industry experience preferred.Experience in molecular IVD product development under Design Control, including assay verification, integration and testing, transfer to production.Expertise in the development of instrument and equipment qualification processes.Experience with a variety of laboratory equipment and test methods, including liquid handlers and lab automation.Experience with nucleic acid extraction technologies, best practices for DNA handling and analytical testing platforms.Experience product transfer and verification in an FDA-regulated environment desired.Practical knowledge of Next Generation Sequencing sample preparation workflows and applications preferred.Excellent personal task management skills and a high level of self-motivation.Excellent verbal and written communication skills and willingness to collaborate cross-functionally across Quality, Regulatory, Operations and Development teams.
Grail Menlo Park, CA, USA
Jan 09, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com As a key member of the quality team at GRAIL, the Associate Director, Design Control will be responsible for leading and managing the Design Control efforts. The successful candidate will manage all elements of design control and documentation; risk management, development, planning, input, output, review, verification, validation, change control, specifications, SOPs, protocols, and reports. This individual will lead and/or support all quality engineering, qualification and validation activities of the product life cycle and maintain a Design History File (DHF) for the device in accordance with the approved design plan, procedures and regulations.  The individual will apply “systems” thinking and knowledge of systems, reliability, risk management, standards and design V&V engineering, test method development principles, practices and implementation to support new and sustaining projects. They will establish the vision, develops procedures, and facilitate the execution of activities within GRAIL. They will work creatively and collaboratively to engineer fit-for-purpose processes compliant with Quality regulations. You Will: Collaborate with functional leads to design and build Quality System processes to work with GRAIL’s existing systems and product pipelines.Design, develop, approve, and implement Design Control Quality Systems SOPs, forms, reports, protocols, and documents associated with design control and Validations processes.Approve changes to process and new design activities.Provide QA support for Test method assay Product development from feasibility through transfer into commercialization.Perform and review/approve design control and risk management activities. Work closely with research and development organizations to ensure potential product issues are identified and addressed in the design.Work effectively and influence multiple functions (R&D, Operations, Product/Program, Regulatory, Supply Chain, Medical, etc.) to ensure design control expectations are met.Develop/oversee the FMEAs and other risk assessment processes and documentation (as required). Ensure Quality Risk Management Files are in alignment with 21CFR Part 820 design control and risk management requirements of ISO 14971:2012.Conduct risk assessments and create/revise risk management documents as required by Standard Operating Procedures, FDA, and other medical device regulations.Lead assessment of hazard analyses, design risk assessments, use of risk assessments, system risk assessments, and process risk assessments.Work with product development teams to assess design changes from a systems perspective, identifying risks, delivering design mitigations and evaluating the effectiveness of the risk control measures.Represent the company as a Quality Assurance subject matter expert during internal and external regulatory inspections.Ensure design control documentation and requirements are met.Anticipate and manage project risks and issues, and provide specific mitigation and corrective action strategies.Work on complex technical problems, utilize quality engineering methods and provide innovative solutions.Perform 3rd party management activities such as review of design control deliverables, assessment of supplier changes, supplier controls (corrective actions), quality agreements, relationship development.Monitor, track/trend all KPI and periodically provide a summary report to Sr. management including participation in Management Review meetings and Material Review Board (MRB).Facilitate Design review activities, process capabilities, including validation in partnership with Engineering, Product/Program team, and Clinical Development team, etc.Provide coaching to QA, product development key stakeholders personnel on Quality Systems requirements and process improvement methodologies. You Will: Minimum of a Bachelor of Science Degree in Engineering or scientific field with at least 10 years of validation experience in the medical device or combination products industry.ASQ, CQE, CQA, black belt or other equivalent certification is preferred.At least 5 years of direct managerial responsibility leading all aspects of Design Control and Validation for Medical DevicesExtensive experience and understanding of design, development, verification and validation processes.Exceptional working knowledge and understanding of Device and Combination products regulations (21CFR 820 and ISO 13485), Risk Assessment (ISO 14971, ICHQ 9), ASTM standards and other ICH guidance.Proven experience in managing FMEAs, Lean/Six Sigma projects, black belt, process validation, process capability, statistical analysis and application of statistical methods (JMP, Minitab).Excellent verbal, written, communication and proficient computer skills, specifically with statistical software and Microsoft Office Suite including Word, Excel, PowerPointMust be able to work in a biohazard environment and comply with safety policies and standards outlined in the Safety Manual.
Grail Menlo Park, CA, USA
Jan 09, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com GRAIL is seeking a Director of Medical Communications to join the Clinical Development/Medical Affairs (CDMA) department. This person will drive our publication strategy, and, more broadly, our medical communications strategy, and will be responsible for ensuring the publication and/or presentation of our key scientific, clinical, and technological advances in peer-reviewed journals and/or scientific/medical congresses. This role will work closely with numerous other functions, including corporate communications, R&D, clinical development, data science, and biostatistics. The ideal candidate is a strategic thinker who can also roll up their sleeves and get work done, is detail-oriented, motivated, independent, and able to respond quickly to evolving needs. This position will be based in Menlo Park, California, will have 1-2 direct reports, and will report to the Senior Director of Medical Communications.  You Will: Drive publication strategy, planning, and execution Evolve and execute GRAIL’s publication strategyCreate and coordinate the development and review of scientific abstracts, posters, and presentationsDevelop and support external presentationsManage Medical Communication agency budget and day-to-day interactionsOversee publication compliance with company and industry regulations and policies, including ICMJE and GPP3Assess the impact of the publication strategy and tacticsDrive monthly Publication Team meetingsPlan, support, and attend scientific conferences and medical meetingsEvolve GRAIL’s scientific platform (including potential to develop a new platform)Work with corporate communications on external communication strategy, ensuring press releases, FAQs, and other documents/slide decks are scientifically/medically accurate and messaging is alignedAs a key member of the Medical Affairs team, participate in Medical Affairs strategic planningSupport pre- and peri-launch activities (eg, participate in launch teams) Help develop and maintain Core Data Decks, Disease State Decks, FAQ documents, and training materials for the entire portfolioIdentify, develop, and maintain relationships with the medical community, thought leaders, and treatment advocatesSupervise 1-2 team members Review study reports, clinical protocols, and summary dossiers for content and accuracy Your Background Should Include: Advanced degree preferred (PhD, PharmD, MD)7+ years of experience in medical affairs (publication planning)Successful track record of leading and implementing publication strategy, including preparation of abstracts, manuscripts, posters, and presentation slide decks, managing external reviews and revisions, and the submission process for scientific conferences and journalsProven understanding of industry best practices, including ICMJE and GPP3; CMPP-certification preferredCommitment to complianceExceptional writing skills and attention to detailExcellent research skills and quick learner Ability to efficiently manage time and priorities, and adapt to a fast-paced environmentExcellent leadership and communications skills with experience in externally facing roles, including interactions with key opinion leaders, clinical study site investigators, expert advisors, and other professionals Experience in genomics, diagnostics, oncology, or other applied medical fields a plusExperience as an exceptional team player with a demonstrated track record of success in cross-functional team environment and leadership rolesExcellent leadership and communication skills
Grail Menlo Park, CA, USA
Jan 09, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com GRAIL is seeking a Scientist II in the Assay Development team to contribute to the development of GRAIL’s groundbreaking cancer screening products. You will be responsible for leading wet-lab research and development studies in support of product development goals, including the design, planning, execution, and analysis of complex experiments.  The ideal candidate is a technically-rigorous team player with strong experience in NGS assay development, genomic data analysis, and outstanding communication skills. You Will: Technical lead on studies related to the design, development and verification of NGS assay processes used in clinical laboratory products Drive development efforts to optimize assay performance and improve laboratory processesDevelop experimental plans that support study objectivesExecute laboratory experiments in collaboration with more junior technical staff to generate high quality data by following best practices of assay and instrument operationsPerform data analysis and document study outcomes and conclusionsSummarize, present and document study outcomes to key stakeholdersCollaborate with different functions including bioinformatics, data science, biostatistics, clinical development, quality, and clinical operationsSupport training of junior Research Associates Your Background Should Include: PhD degree in Molecular Biology, Genetics, Cancer Genomics or relevant disciplines with 3+ years of postdoctoral or industry experienceStrong hands-on laboratory experience and in-depth knowledge of Illumina NGS workflow including nucleic acids extraction, library preparation, sequencing.  Experience with the development and optimization of NGS assay protocols a plusExperienced with standard analytical nucleic acid techniques (e.g, qPCR, Nanodrop, Fragment Analyzer, ddPCR) Experience with automated liquid handlersExperience with statistical programming or software (e.g, R, JMP) a plus Experience with Design of Experiment (DOE) a plusAttention to detail, safety, good laboratory practice, and good documentation practiceStrong verbal and written communication skills and willingness to collaborate cross-functionally in a fast paced and dynamic environment
Grail Menlo Park, CA, USA
Jan 09, 2020
GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. GRAIL is focused on alleviating the global burden of cancer by developing pioneering technology to detect and identify multiple deadly cancer types early. The company is using the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to enhance the scientific understanding of cancer biology, and to develop its multi-cancer early detection blood test. GRAIL is located in Menlo Park, California. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies. For more information, please visit www.grail.com The Senior Accountant is an experienced level position in the Finance organization. They are an accounting and financial professional with the experience to excel in a high-growth private or public company. They have experience preparing and administering accounting operations and the capacity for ad hoc analysis as new opportunities arise. Their diverse experience and will be to support and enable the Finance organization to meet the needs of a growing company. You Will: Own several areas of the GL, including consolidations, inventory, fixed assets and certain accruals.Document and maintain inventory sub-processes.Assist with the execution and/or supervision of inventory existence procedures (wall-to-wall physical inventories and/or cycle count procedures).Lead the implementation efforts around relevant accounting systems Prepare journal entries, balance sheet reconciliations, technical analysis, and reports for period-end close and audit.Help design & maintain a thorough system of accounting processes, policies and controls designed to accurately and efficiently close the books.Develop a thorough understanding of the Company’s business to all aspects of inventory accounting, building and reporting COGS modelsManaging relationships with existing stakeholders and forming new relationships with internal groups to ensure excellent customer service.Interface with external accountants during audits.Assist on projects and ad hoc assignments as needed. Your Background Should Include: At least 6 years of experience applying accounting and financial best-practices in a public or private company environment.Experience implementing accounting systems and processes in a growing environment.Excellent professional written and verbal communication and interpersonal skills.Experience leveraging analytics and project management skills.Experience with life sciences companies with inventory and manufacturing processes Ability to prioritize assignments, deal with interruptions, and meet deadlines.Advanced Excel and Google Suite skills.